Description
NURAN 50 CAPSULES
is a prescription medication manufactured by ANVIS, containing Pregabalin 50 mg in each capsule. The pack includes 1 x 10 capsules.
Active ingredient:
- Pregabalin 50 mg – an anticonvulsant and neuropathic pain agent.
Mechanism of action:
Pregabalin binds to the α2δ subunit of voltage-gated calcium channels in the central nervous system. This reduces calcium influx into nerve terminals, thereby decreasing the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. The result is reduced neuronal hyperexcitability, which helps in controlling seizures, neuropathic pain, and anxiety symptoms.
Indications:
- Neuropathic pain associated with diabetic neuropathy, post-herpetic neuralgia, or spinal cord injury
- Adjunctive therapy for partial seizures
- Generalized anxiety disorder (GAD)
- Fibromyalgia (in some treatment guidelines)
Benefits:
- Effective in reducing chronic neuropathic pain
- Improves sleep disturbances linked to nerve pain
- Provides anxiolytic effects in patients with GAD
- Convenient capsule form for oral administration
Packaging:
- Box of 1 x 10 capsules (blister pack)
- Strength: 50 mg
Safety notes:
- Should be used under medical supervision
- May cause dizziness, somnolence, or blurred vision
- Dose adjustments may be required in renal impairment
- Not recommended for abrupt discontinuation due to risk of withdrawal symptoms
Market positioning:
Compared to gabapentin, pregabalin offers higher bioavailability and faster onset of action, making it a preferred choice in many neuropathic pain management protocols.
